A Patient with carcinoma in situ


  • Male, 75 years old


  • Urgency and dysuria for the past 6 months

Medical history

  • Partial gastrectomy for gastric cancer several years ago
  • Significant comorbidities (Charlson Comorbidity Index = 5)


  • Urinary cytology: two specimens registered atypical urothelial cells and papillary clusters
  • White light flexible cystoscopy: No tumors or abnormalities detected
  • Hexvix® blue-light cystoscopy revealed two suspicious areas, biopsies taken

Case1_Img_1Case1_Img_2   Case1_Img_3Case1_Img_4

Images show the comparison between conventional white light and Hexvix® blue-light cystoscopy at two sites

Histologic results

  • Carcinoma in situ (CIS)

Therapeutic approach

  • 1 year BCG instillation


  • No recurrence or new lesion detected