Hexvix toolbox


Fact sheet Hexvix
Fact sheet Bladder Cancer

Cystoscopy video

A transurethral resection of the bladder conducted by Mosjøen Hospital, Norway.

Bladder pictures

CIS in white light and blue-light
Click on this link to download high resolution bladder pictures in white and blue-light:
Bladder-pictures.zip (15MB)
The images are numbered so that the images with matching names and numbers are taken from the same patient in the same area in both white and blue-light mode. Here you can see the difference in tumor detection. The pictures have been provided to us in courtesy of Professor Dirk Zaak, Associate Professor, Dept of Urology, University of Munich, Germany.

Here you can see the inside of a bladder with suspected bladder cancer. The patient has received Hexvix® and you can see cancer cells lighting up red on a blue background when visualized in the blue-light mode.


External resources

Here we have gathered some resources that you may find useful in your work

National Guidelines

Swedish National Guidelines – Nationellt Vårdprogram (August 2015)
On page 23-24 you will find the guidelines regarding the use of Hexvix®

Norwegian National Guidelines – Nasjonalt Handlingsprogram (April 2013)
On page 23 you will find the guidelines regarding the use of Hexvix®

Danish National Guidelines – Nationale kliniske retningsliner (May 2015)
On page 20 you will find the guidelines regarding the use of Hexvix®

Clinical Summaries

Burger et al. 2013
Photodynamic diagnosis of non-muscle-invasive bladder cancer with hexaminolevulinate cystoscopy: a meta-analysis of detection and recurrence based on raw data.
Grossman et al. 2012
Long-term decrease in bladder cancer recurrence with Hexaminolevulinate enabled fluorescence cystoscopy.
Geavlete et al. 2011
Treatment changes and long-term recurrence rates after Hexaminolevulinate (Hexvix®) fluorescence cystoscopy: does it really make a difference in patients with non-muscle-invasive bladder cancer (NMIBC)?
Hermann et al. 2011
Fluorescence guided trans-urethral resection of the bladder reduces bladder tumor recurrence due to less residual tumor tissue in Ta/T1 patients: a randomized 2-center study.
Stenzl et al. 2010
Hexaminolevulinate guided fluorescence cystoscopy reduces recurrence in patients with non-muscle invasive bladder cancer.
Grossman et al. 2007
A phase III, multicenter comparison of Hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of superficial papillary lesions in patients with bladder cancer.
Jocham et al. 2005
Improved detection and treatment of bladder cancer using Hexaminolevulinate imaging: A prospective, phase III multicenter study.
Schmidbauer et al. 2004
Improved detection of urothelial carcinoma in situ with Hexaminolevulinate fluorescence cystoscopy.
Jichlinski et al. 2003
Hexylaminolevulinate fluorescence cystoscopy: a new diagnostic tool for the photodiagnosis of superficial bladder cancer – a multicenter study.