STRONG RECOMMENDATIONS FOR BLUE LIGHT CYSTOSCOPY WITH HEXVIX® IN NEW FRENCH GUIDELINES

Oslfranceo, Norway, November, 21 2016: Photocure ASA (OSE:PHO) announced today that new 2016 French National Guidelines for the management of Bladder Cancer includes its Blue Light Cystoscopy (BLC) with Hexvix®The new guidelines have been presented on November 17th, during Association of French Urologists (AFU) National Meeting, Paris, France published on line in Progres en urologie.  Please click here for an abstract of the guidelines.

 The French guidelines recommend BLC with Hexvix® for the first bladder cancer resection (TURBT) in essentially all patients and for consecutive TURBT’s in the majority of patients. The recommendations are at an evidence level Grade B, demonstrating the strong clinical data supporting BLC with Hexvix®.

 “The Association of French Urology National Bladder Cancer Guidelines for the management of patients with bladder cancer were last released in 2013.  One of the biggest differences since the last guideline is that it now includes the situations BLC with Hexvix® can be used to reduce the risk of recurrence of NMIBC. The strong recommendation for use of blue light cystoscopy with Hexvix® should result in contributing to increasing the level of urological care for the management of patients with bladder cancer in France,” said  M. Roupret, during his presentation on the guidelines at the AFU meeting, Professor of Urology Pitié-Salpétrière – Hôpitaux de Paris University and one of the authors of the guidelines.

 “The updated French National Guidelines recommending BLC with Hexvix® for such a wide range of patient types will result in BLC with Hexvix® being seen as standard of care. It is especially encouraging to see the strong recommendation for using BLC at the very critical first TURBT, which allows for the most correct staging and grading, which is crucial for the optimal follow-up and management of the patient. The recommendation for use in the first TURBT is also supported by Hexvix® cost effectiveness data developed for French conditions published in 20151,” commented Kjetil Hestdal, MD, PhD, President and CEO, Photocure ASA.

 In 2011, Photocure entered into a strategic collaboration with Ipsen to commercialize Hexvix®, its flagship product for the diagnosis and management of bladder cancer, worldwide except in the United States of America (USA) and the Nordic region. This technology represents a significant improvement for urologists and their patients. Ipsen is notably responsible for the commercialization of Hexvix® in France.

References

1. Roupret et al, Progres en urologie (2015) 25, 256-264: Cost effectiveness of TURBT of the bladder with blue light in patients with non-muscle invasive bladder cancer in France.

 2. Globocan.  Incidence/mortality by population.  Available at: http://globocan.iarc.fr/Pages/bar_pop_sel.aspx (accessed March 2015)

3. Leal et al, Eur Urol 2016; 69: 438-447